Welcome to Şen Lab
Receptorology Structural Biology Protein Chemistry

Unraveling the mysteries of physical and chemical regulatory
mechanisms in protein function

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ABOUT US

Our research interests lie in the structural and functional basis of receptor–ligand interactions, which are relevant to human health and disease. Much of our studies aim to elucidate the molecular recognition properties governing receptor interactions with a ligand, and subsequent molecular events that couple ligand recognition to receptor activation. Many of the systems we study are related to the interactions between the host cell and environmental cues.

Structural studies are then complemented by functional approaches using molecular biology and protein engineering to dissect structural information, design proteins or peptides with modified specificities and activities, and ultimately contribute to the development of biologics with therapeutic potential.

Inside the Şen Lab

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What We Do

The Şen Lab is a multidisciplinary group that encompasses people from
various talents and backgrounds.

Molecular Biology

The study of life through the lenses of macromolecules.

Biochemistry

Metabolic and chemical processes within living organisms.

Biophysics

Physical phenomena in life, and the mathematics that explain them.